3/31/2024 0 Comments Hippocampus anatomy model networkHere, I instantiate a neural network model of cholinergic effect in the hippocampus, capable of executing pattern separation tasks under various levels of simulated cholinergic activity. While there exist previous computational models of cholinergic activity in the hippocampus (Hasselmo, 2006), they lack the breadth and ability of more recent hippocampal models which incorporate theta rhythms and error-driven learning, increasing model capacity and yielding more robust results (Ketz et al., 2013). Computational Neural Network Model of Cholinergic Activity in the HippocampusĪn increasing body of research indicates that high cholinergic states in the hippocampus improve encoding ability while not affecting retrieval.
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